Filed in archive
Digestive Health
by Florence Cardinal on April 3, 2007

The latest to go, as reported in the New York Times, is Zelnorm (tegasarod):
The maker of Zelnorm, a medicine that treats constipation-related irritable bowel syndrome, stopped selling the drug Friday after federal drug officials concluded that it might cause heart attacks and strokes.
eDrugs.com describes the drug this way:
Tegaserod is used to treat severe, chronic, irritable bowel syndrome (IBS) in women who have constipation as their main bowel problem (constipation-predominant). It is also used to treat chronic idiopathic constipation in patients less than 65 years of age.
But there were problems with this drug even before the latest news. This from Web MD:
The FDA says Zelnorm has been associated with serious cases of diarrhea as well as instances of ischemic colitis -- a medical condition where blood flow is reduced to the intestines.
Permalink: Irritable Bowel Drug Withdrawn
Tags:
constipation
irritable
bowel
syndrome
Zelnorm
tegasarod
heart
attack
strokes
health
irritable+bowel
Trackback: http://publish.creative-weblogging.com/publish/mt-tb.pl/61095
Mr Wong
Vote for Irritable Bowel Drug Withdrawn:
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Rating: 10.00 out of 2 vote(s) cast.
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Response from:
ThxRehab
(05/29/07 1:22am)
Tegaserod increases the action of serotonin (a body chemical) in the intestines. This speeds the movement of stools (bowel movements) through the bowels.
Response from:
Florence
(05/29/07 10:20am)
And this, I would thin, would cause diahrea which is already a problem with irritable bowel.
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